Friday, November 30, 2012

ScienceDaily: Gene News

ScienceDaily: Gene Newshttp://www.sciencedaily.com/news/health_medicine/genes/ Genes and Genetics News. Read today's medical research in genetics including what can damage genes, what can protect them, and more.en-usThu, 29 Nov 2012 03:04:26 ESTThu, 29 Nov 2012 03:04:26 EST60ScienceDaily: Gene Newshttp://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/health_medicine/genes/ For more science articles, visit ScienceDaily.Risk of childhood obesity can be predicted at birthhttp://www.sciencedaily.com/releases/2012/11/121128182739.htm A simple formula can predict at birth a baby?s likelihood of becoming obese in childhood, according to a new study.Wed, 28 Nov 2012 18:27:27 ESThttp://www.sciencedaily.com/releases/2012/11/121128182739.htmPonatinib acts against the most resistant types of chronic myeloid leukemiahttp://www.sciencedaily.com/releases/2012/11/121128182719.htm Phase I trial shows third-generation drug helps patients after other treatments fail.Wed, 28 Nov 2012 18:27:27 ESThttp://www.sciencedaily.com/releases/2012/11/121128182719.htmDouble duty: Immune system regulator found to protect brain from effects of strokehttp://www.sciencedaily.com/releases/2012/11/121128143549.htm A small molecule known to regulate white blood cells has a surprising second role in protecting brain cells from the deleterious effects of stroke, researchers report. The molecule, microRNA-223, affects how cells respond to the temporary loss of blood supply brought on by stroke -- and thus the cells' likelihood of suffering permanent damage.Wed, 28 Nov 2012 14:35:35 ESThttp://www.sciencedaily.com/releases/2012/11/121128143549.htmScientists pair blood test and gene sequencing to detect cancerhttp://www.sciencedaily.com/releases/2012/11/121128142651.htm Scientists have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients for recurrence and find residual cancer left after surgery.Wed, 28 Nov 2012 14:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121128142651.htmResearchers increase understanding of genetic risk factor for type 1 diabeteshttp://www.sciencedaily.com/releases/2012/11/121128132355.htm Researchers have demonstrated how a genetic variant associated with type 1 diabetes and other autoimmune diseases influences susceptibility to autoimmunity.Wed, 28 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121128132355.htmHuman genetic variation recent, varies among populationshttp://www.sciencedaily.com/releases/2012/11/121128132259.htm Nearly three-quarters of mutations in genes that code for proteins -- the workhorses of the cell -- occurred within the past 5,000 to 10,000 years, fairly recently in evolutionary terms, said genomic and genetic experts.Wed, 28 Nov 2012 13:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121128132259.htmScientists uncover a novel cooperative effort to stop cancer spreadhttp://www.sciencedaily.com/releases/2012/11/121128122041.htm Scientists have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site.Wed, 28 Nov 2012 12:20:20 ESThttp://www.sciencedaily.com/releases/2012/11/121128122041.htmChanges in nerve cells may contribute to the development of mental illnesshttp://www.sciencedaily.com/releases/2012/11/121128122035.htm Reduced production of myelin, a type of protective nerve fiber that is lost in diseases like multiple sclerosis, may also play a role in the development of mental illness, according to new research.Wed, 28 Nov 2012 12:20:20 ESThttp://www.sciencedaily.com/releases/2012/11/121128122035.htmFirst success of targeted therapy in most common genetic subtype of non-small cell lung cancerhttp://www.sciencedaily.com/releases/2012/11/121128121505.htm Chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer, new research suggests.Wed, 28 Nov 2012 12:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121128121505.htmImmune system could play a central role in age-related macular degenerationhttp://www.sciencedaily.com/releases/2012/11/121128093919.htm Changes in how genes in the immune system function may result in age-related macular degeneration (AMD), the leading cause of visual impairment in older adults. The findings are epigenetic in nature, meaning that the underlying DNA is normal but gene expression has been modified, likely by environmental factors, in an adverse way. Environmental factors associated with AMD include smoking, diet, and aging. This is the first epigenetic study revealing the molecular mechanisms for any eye disease.Wed, 28 Nov 2012 09:39:39 ESThttp://www.sciencedaily.com/releases/2012/11/121128093919.htmMany flame retardants in house dust at unsafe levels, study findshttp://www.sciencedaily.com/releases/2012/11/121128093810.htm In a new study of the largest number of flame retardants ever tested in homes, researchers found that most houses had levels of at least one flame retardant that exceeded a federal health guideline.Wed, 28 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121128093810.htmHow infidelity helps nieces and nephews: Men may share more genes with sisters' kids than cheating wife's kidshttp://www.sciencedaily.com/releases/2012/11/121127190021.htm A new study produced new mathematical support for a theory that explains why men in some cultures often feed and care for their sisters? children: where extramarital sex is common and accepted, a man?s genes are more likely to be passed on by their sister?s kids than by their wife?s kids.Tue, 27 Nov 2012 19:00:00 ESThttp://www.sciencedaily.com/releases/2012/11/121127190021.htmGene linked to respiratory distress in babieshttp://www.sciencedaily.com/releases/2012/11/121127130256.htm Some infants are more susceptible to potentially life-threatening breathing problems after birth, and rare, inherited DNA differences may explain why, according to new research.Tue, 27 Nov 2012 13:02:02 ESThttp://www.sciencedaily.com/releases/2012/11/121127130256.htmNew understanding of X chromosome inactivationhttp://www.sciencedaily.com/releases/2012/11/121127101534.htm Scientists have broadened our understanding of how cells regulate silencing of the X chromosome in a process known as X-inactivation.Tue, 27 Nov 2012 10:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121127101534.htmNew mechanism for cancer progression discoveredhttp://www.sciencedaily.com/releases/2012/11/121127094311.htm Researchers have discovered an alternative mechanism for activating rhe oncogene Ras that does not require mutation or hormonal stimulus.Tue, 27 Nov 2012 09:43:43 ESThttp://www.sciencedaily.com/releases/2012/11/121127094311.htmProtein injection points to muscular dystrophy treatmenthttp://www.sciencedaily.com/releases/2012/11/121127094248.htm Scientists have discovered that injecting a novel human protein into muscle affected by Duchenne muscular dystrophy significantly increases its size and strength, findings that could lead to a therapy akin to the use of insulin by diabetics.Tue, 27 Nov 2012 09:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121127094248.htmChemical 'switches' for neurodegenerative diseases discoveredhttp://www.sciencedaily.com/releases/2012/11/121127093951.htm Researchers have identified and ?switched off? a chemical chain that causes neurodegenerative diseases such as Huntington?s disease, amyotrophic lateral sclerosis and dementia. The findings could one day be of particular therapeutic benefit to Huntington?s disease patients.Tue, 27 Nov 2012 09:39:39 ESThttp://www.sciencedaily.com/releases/2012/11/121127093951.htmGene that causes tumor disorder linked to increased breast cancer riskhttp://www.sciencedaily.com/releases/2012/11/121127093855.htm New research showing a more than four-fold increase in the incidence of breast cancer in women with neurofibromatosis-1 (NF1) adds to growing evidence that women with this rare genetic disorder may benefit from early breast cancer screening with mammograms beginning at age 40, and manual breast exams as early as adolescence.Tue, 27 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121127093855.htmMetabolic protein launches sugar feast that nurtures brain tumorshttp://www.sciencedaily.com/releases/2012/11/121126164003.htm PKM2 slips into nucleus to promote cancer; potential biomarker and drug approach discovered.Mon, 26 Nov 2012 16:40:40 ESThttp://www.sciencedaily.com/releases/2012/11/121126164003.htmPossible new treatment for Ewing sarcomahttp://www.sciencedaily.com/releases/2012/11/121126142855.htm Discovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously unknown mechanism behind it, come hand-in-hand in a new study.Mon, 26 Nov 2012 14:28:28 ESThttp://www.sciencedaily.com/releases/2012/11/121126142855.htmSurvival gene may be key to controlling HIV and hepatitishttp://www.sciencedaily.com/releases/2012/11/121126131349.htm A newly discovered gene that is essential for embryo survival could also hold the key to treating and potentially controlling chronic infections such as HIV, hepatitis and tuberculosis. The gene, called Arih2, is fundamental to the function of the immune system -- making critical decisions about whether to switch on the immune response to an infection.Mon, 26 Nov 2012 13:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121126131349.htmMicrobial 'missing link' discovered after man impales hand on tree branchhttp://www.sciencedaily.com/releases/2012/11/121126110737.htm Two years ago, a 71-year-old Indiana man impaled his hand on a branch after cutting down a dead tree. The wound caused an infection that led scientists to discover a new bacterium and solve a mystery about how bacteria came to live inside insects.Mon, 26 Nov 2012 11:07:07 ESThttp://www.sciencedaily.com/releases/2012/11/121126110737.htmTransposable elements reveal a stem cell specific class of long noncoding RNAshttp://www.sciencedaily.com/releases/2012/11/121125192838.htm Over a decade after sequencing the human genome, it has now become clear that the genome is not mostly ?junk? as previously thought. In fact, the ENCODE project consortium of dozens of labs and petabytes of data have determined that these ?noncoding? regions house everything from disease trait loci to important regulatory signals, all the way through to new types of RNA-based genes.Sun, 25 Nov 2012 19:28:28 ESThttp://www.sciencedaily.com/releases/2012/11/121125192838.htmNew molecular culprit linked to breast cancer progressionhttp://www.sciencedaily.com/releases/2012/11/121124090511.htm Researchers have uncovered a protein ?partner? commonly used by breast cancer cells to unlock genes needed for spreading the disease around the body. A report on the discovery details how some tumors get the tools they need to metastasize.Sat, 24 Nov 2012 09:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121124090511.htmNew insights into virus proteome: Unknown proteins of the herpesvirus discoveredhttp://www.sciencedaily.com/releases/2012/11/121123092132.htm The genome encodes the complete information needed by an organism, including that required for protein production. Viruses, which are up to a thousand times smaller than human cells, have considerably smaller genomes. Using a type of herpesvirus as a model system scientists have shown that the genome of this virus contains much more information than previously assumed. The researchers identified several hundred novel proteins, many of which were surprisingly small.Fri, 23 Nov 2012 09:21:21 ESThttp://www.sciencedaily.com/releases/2012/11/121123092132.htmScientists describe elusive replication machinery of flu viruseshttp://www.sciencedaily.com/releases/2012/11/121122152928.htm Scientists have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy techniques to ?see? one of influenza?s essential protein complexes in unprecedented detail. The images generated in the study show flu virus proteins in the act of self-replication, highlighting the virus?s vulnerabilities that are sure to be of interest to drug developers.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152928.htmProtein folding: Look back on scientific advances made as result of 50-year old puzzlehttp://www.sciencedaily.com/releases/2012/11/121122152910.htm Fifty years after scientists first posed a question about protein folding, the search for answers has led to the creation of a full-fledged field of research that led to major advances in supercomputers, new materials and drug discovery, and shaped our understanding of the basic processes of life, including so-called "protein-folding diseases" such as Alzheimer's, Parkinson's and type II diabetes.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152910.htmStep forward in regenerating and repairing damaged nerve cellshttp://www.sciencedaily.com/releases/2012/11/121121145638.htm Researchers recently uncovered a nerve cell's internal clock, used during embryonic development. This breakthrough could lead to the development of new tools to repair and regenerate nerve cells following injuries to the central nervous system.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145638.htmArchitecture of rod sensory cilium disrupted by mutationhttp://www.sciencedaily.com/releases/2012/11/121121145621.htm Using a new technique called cryo-electron tomography, scientists have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145621.htmAging: Scientists further unravel telomere biologyhttp://www.sciencedaily.com/releases/2012/11/121121130933.htm Researchers have resolved the structure of that allows a telomere-related protein, Cdc13, to form dimers in yeast. Mutations in this region of Cdc13 put the kibosh on the ability of telomerase and other proteins to maintain telomeres.Wed, 21 Nov 2012 13:09:09 ESThttp://www.sciencedaily.com/releases/2012/11/121121130933.htmDrug resistance biomarker could improve cancer treatmenthttp://www.sciencedaily.com/releases/2012/11/121121130811.htm Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a new study. The study reveals a biomarker that can predict responses to cancer drugs and offers a strategy to treat drug-resistant tumors based on their genetic signature.Wed, 21 Nov 2012 13:08:08 ESThttp://www.sciencedaily.com/releases/2012/11/121121130811.htmGenome packaging: Key to breast cancer developementhttp://www.sciencedaily.com/releases/2012/11/121121130703.htm Two recent studies delve into the role of chromatin modifying enzymes and transcription factors in tumour cells. In one, it was found that the PARP1 enzyme activated by kinase CDK2 is necessary to induce the genes responsible for the proliferation of breast cancer cells in response to progesterone. In another, extensive work has been undertaken to identify those genes activated by the administration of progesterone in breast cancer, the sequences that can be recognized and how these genes are induced.Wed, 21 Nov 2012 13:07:07 ESThttp://www.sciencedaily.com/releases/2012/11/121121130703.htmShort DNA strands in genome may be key to understanding human cognition and diseaseshttp://www.sciencedaily.com/releases/2012/11/121121130643.htm Previously discarded, human-specific ?junk? DNA represents untapped resource in the study of diseases like Alzheimer?s and autism.Wed, 21 Nov 2012 13:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121121130643.htmBiomarking time: Methylome modifications offer new measure of our 'biological' agehttp://www.sciencedaily.com/releases/2012/11/121121130633.htm In a new study, researchers describe markers and a model that quantify how aging occurs at the level of genes and molecules, providing not just a more precise way to determine how old someone is, but also perhaps anticipate or treat ailments and diseases that come with the passage of time.Wed, 21 Nov 2012 13:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121121130633.htmKidney tumors have a mind of their ownhttp://www.sciencedaily.com/releases/2012/11/121121104552.htm New research has found there are several different ways that kidney tumors can achieve the same result -- namely, grow.Wed, 21 Nov 2012 10:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121121104552.htmMechanism to repair clumped proteins explainedhttp://www.sciencedaily.com/releases/2012/11/121121104416.htm Clumped proteins can be dissolved with the aid of cellular repair systems -- a process of critical importance for cell survival especially under conditions of stress. Researchers have now decrypted the fundamental mechanism for dissolving protein aggregates that involves specific molecular chaperones.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104416.htmNovel mechanism through which normal stromal cells become cancer-promoting stromal cells identifiedhttp://www.sciencedaily.com/releases/2012/11/121121104401.htm New understanding of molecular changes that convert harmless cells surrounding ovarian cancer cells into cells that promote tumor growth and metastasis provides potential new therapeutic targets for this deadly disease, according to new research.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104401.htmNew test for tuberculosis could improve treatment, prevent deaths in Southern Africahttp://www.sciencedaily.com/releases/2012/11/121120194932.htm A new rapid test for tuberculosis (TB) could substantially and cost-effectively reduce TB deaths and improve treatment in southern Africa -- a region where both HIV and tuberculosis are common.Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194932.htmEvolution of human intellect: Human-specific regulation of neuronal geneshttp://www.sciencedaily.com/releases/2012/11/121120194926.htm A new study has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory differences distinguish us from other primates, including monkeys and apes, and as neurons are at the core of our unique cognitive abilities, these features may ultimately hold the key to our intellectual prowess (and also to our potential vulnerability to a wide range of 'human-specific' diseases from autism to Alzheimer's).Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194926.htmRibosome regulates viral protein synthesis, revealing potential therapeutic targethttp://www.sciencedaily.com/releases/2012/11/121120132906.htm Rather than target RNA viruses directly, aiming at the host cells they invade could hold promise, but any such strategy would have to be harmless to the host. Now, a surprising discovery made in ribosomes may point the way to fighting fatal viral infections such as rabies.Tue, 20 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121120132906.htmHow does antibiotic resistance spread? Scientists find answers in the nosehttp://www.sciencedaily.com/releases/2012/11/121120121835.htm Microbiologists studying bacterial colonization in mice have discovered how the very rapid and efficient spread of antibiotic resistance works in the respiratory pathogen, Streptococcus pneumoniae (also known as the pneumococcus). The team found that resistance stems from the transfer of DNA between bacterial strains in biofilms in the nasopharynx, the area just behind the nose.Tue, 20 Nov 2012 12:18:18 ESThttp://www.sciencedaily.com/releases/2012/11/121120121835.htmScientists identify inhibitor of myelin formation in central nervous systemhttp://www.sciencedaily.com/releases/2012/11/121120100155.htm Scientists have discovered another molecule that plays an important role in regulating myelin formation in the central nervous system. Myelin promotes the conduction of nerve cell impulses by forming a sheath around their projections, the so-called axons, at specific locations -- acting like the plastic insulation around a power cord.Tue, 20 Nov 2012 10:01:01 ESThttp://www.sciencedaily.com/releases/2012/11/121120100155.htm'Obese but happy gene' challenges the common perception of link between depression and obesityhttp://www.sciencedaily.com/releases/2012/11/121120084725.htm Researchers have discovered new genetic evidence about why some people are happier than others. The scientists have uncovered evidence that the gene FTO -- the major genetic contributor to obesity -- is associated with an eight per cent reduction in the risk of depression. In other words, it's not just an obesity gene but a "happy gene" as well.Tue, 20 Nov 2012 08:47:47 ESThttp://www.sciencedaily.com/releases/2012/11/121120084725.htmTelomere lengths predict life expectancy in the wild, research showshttp://www.sciencedaily.com/releases/2012/11/121119213144.htm Researchers have found that biological age and life expectancy can be predicted by measuring an individual's DNA. They studied the length of chromosome caps -- known as telomeres -- in a 320-strong wild population of Seychelles Warblers on a small isolated island.Mon, 19 Nov 2012 21:31:31 ESThttp://www.sciencedaily.com/releases/2012/11/121119213144.htmCancer: Some cells don't know when to stophttp://www.sciencedaily.com/releases/2012/11/121119171403.htm Certain mutated cells keep trying to replicate their DNA -- with disastrous results -- even after medications rob them of the raw materials to do so, according to new research.Mon, 19 Nov 2012 17:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121119171403.htmMultiple sclerosis ?immune exchange? between brain and blood is uncoveredhttp://www.sciencedaily.com/releases/2012/11/121119163301.htm DNA sequences obtained from a handful of patients with multiple sclerosis have revealed the existence of an ?immune exchange? that allows the disease-causing cells to move in and out of the brain.Mon, 19 Nov 2012 16:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121119163301.htmFruit fly studies guide investigators to molecular mechanism frequently misregulated in human cancershttp://www.sciencedaily.com/releases/2012/11/121119132056.htm Changes in how DNA interacts with histones ?- the proteins that package DNA ?- regulate many fundamental cell activities from stem cells maturing into a specific body cell type or blood cells becoming leukemic. These interactions are governed by a biochemical tug of war between repressors and activators, which chemically modify histones signaling them to clamp down tighter on DNA or move aside and allow a gene to be expressed.Mon, 19 Nov 2012 13:20:20 ESThttp://www.sciencedaily.com/releases/2012/11/121119132056.htm3-D light switch for the brain: Device may help treat Parkinson's, epilepsy; aid understanding of consciousnesshttp://www.sciencedaily.com/releases/2012/11/121119114249.htm A new tool for neuroscientists delivers a thousand pinpricks of light to individual neurons in the brain. The new 3-D "light switch", created by biologists and engineers, could one day be used as a neural prosthesis that could treat conditions such as Parkinson's and epilepsy by using gene therapy to turn individual brain cells on and off with light.Mon, 19 Nov 2012 11:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121119114249.htmNew factor of genetic susceptibility to Alzheimer's diseasehttp://www.sciencedaily.com/releases/2012/11/121119104944.htm A large-scale international study has just discovered a gene for susceptibility to a rare disease providing evidence of the heterogeneous aetiology of Alzheimer's disease.Mon, 19 Nov 2012 10:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121119104944.htmBlood cancer gene BCL6 identified as a key factor for differentiation of nerve cells of cerebral cortexhttp://www.sciencedaily.com/releases/2012/11/121119093848.htm The cerebral cortex is the most complex structure in our brain and the seat of consciousness, emotion, motor control and language. In order to fulfill these functions, it is composed of a diverse array of nerve cells, called cortical neurons, which are affected by many neurological and neuropsychiatric diseases. Researchers have opened new perspectives on brain development and stem cell neurobiology by discovering a gene called BCL6 as a key factor in the generation of cortical neurons during embryonic brain development.Mon, 19 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121119093848.htmMinority report: Insight into subtle genomic differences among our own cellshttp://www.sciencedaily.com/releases/2012/11/121118141530.htm Scientists have demonstrated that induced pluripotent stem cells -- the embryonic-stem-cell look-alikes whose discovery a few years ago won this year's Nobel Prize in medicine -- are not as genetically unstable as was thought.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141530.htmSkin cells reveal DNA's genetic mosaichttp://www.sciencedaily.com/releases/2012/11/121118141524.htm The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread in the body's tissues, a finding with profound implications for genetic screening.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141524.htmLikely basis of birth defect causing premature skull closure in infants identifiedhttp://www.sciencedaily.com/releases/2012/11/121118141432.htm Geneticists, pediatricians, surgeons and epidemiologists have identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis premature closure of the bony plates of the skull.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141432.htmDNA packaging discovery reveals principles by which CRC mutations may cause cancerhttp://www.sciencedaily.com/releases/2012/11/121117184658.htm A new discovery concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for researchers who study how gene packaging regulates gene activity, including genes that cause cancer and other diseases.Sat, 17 Nov 2012 18:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121117184658.htmHepatitis C treatment's side effects can now be studied in the labhttp://www.sciencedaily.com/releases/2012/11/121116161059.htm Adverse side effects of certain hepatitis C medications can now be replicated in the lab, thanks to a research team. The new method aids understanding of recent failures of hepatitis C antiviral drugs in some patients, and could help to identify medications that eliminate adverse effects. The findings may aid the development of safer and more effective treatments for hepatitis C and other pathogens such as SARS and West Nile virus.Fri, 16 Nov 2012 16:10:10 ESThttp://www.sciencedaily.com/releases/2012/11/121116161059.htmReconsidering cancer's bad guyhttp://www.sciencedaily.com/releases/2012/11/121116124644.htm Researchers have found that a protein, known for causing cancer cells to spread around the body, is also one of the molecules that trigger repair processes in the brain.Fri, 16 Nov 2012 12:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121116124644.htmGene distinguishes early birds from night owls and helps predict time of deathhttp://www.sciencedaily.com/releases/2012/11/121116124551.htm New research shows that a gene is responsible for a person's tendency to be an early riser or night owl -- and helps determine the time of day a person is most likely to die.Fri, 16 Nov 2012 12:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121116124551.htmClues to cause of kids' brain tumorshttp://www.sciencedaily.com/releases/2012/11/121116091226.htm Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.Fri, 16 Nov 2012 09:12:12 ESThttp://www.sciencedaily.com/releases/2012/11/121116091226.htmArthritis study reveals why gender bias is all in the geneshttp://www.sciencedaily.com/releases/2012/11/121115210541.htm Researchers have pieced together new genetic clues to the arthritis puzzle in a study that brings potential treatments closer to reality and could also provide insights into why more women than men succumb to the disabling condition.Thu, 15 Nov 2012 21:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121115210541.htmClass of RNA molecules protects germ cells from damagehttp://www.sciencedaily.com/releases/2012/11/121115172255.htm Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals. Biologists have now identified one way the body does exactly that.Thu, 15 Nov 2012 17:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121115172255.htm

Source: http://www.sciencedaily.com/rss/health_medicine/genes.xml

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Crafting with Kids: A Birthday Crown : Ideas for Women Home and ...


All kids want something special on their birthdays. You can make the day special by allowing them to make a birthday crown just for them to wear. It is an easy craft and kids will love it.

What You Need:

  • Construction paper
  • Scissors
  • Transparent tape
  • Marker
  • Glue
  • Glitter
  • Stickers

How to Make:

  1. Choose two pieces of construction paper. Cut one of the pieces of paper into 2-inch wide strips. Line the strips end-to-end making one long band. Attach the pieces to one another using transparent tape.
  2. Wrap the band around the child?s head so it covers his or her forehead. Mark about 2 inches beyond where the ends of the band overlap at the back of the child?s head. Cut off any excess paper beyond the mark.
  3. Lay the band out flat on a table and decorate it.Trace six 2-inch squares on the second piece of paper. Add triangles to the top of each square to make shapes that resemble small?houses?and cut out the shapes. Tape the bottom of each shape to the inside edge of the headband so most of the squares stick out the top of the crown.
  4. Decorate the crown by writing the child?s name on the center of the band using glue. Sprinkle glitter over the glue to make the name shimmer and shake off the excess glitter. Add stickers to the crown or draw on smiley faces using markers. Let the glue dry completely.Tape the ends of the band together.
  5. Use two or three long pieces of tape to ensure that the crown stays together all day.

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Source: http://blogs.ideasforwomen.com/blogs/family/2012/11/crafting-with-kids-a-birthday-crown/

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Thursday, November 29, 2012

Environmental group says don't "blow" this opportunity when it comes to wind energy incentives

ROANOKE, Va.?

"Our message today to Congress, don't throw wind off the fiscal cliff," says Sarah Bucci, Environment Virginia.

The clock is ticking and this group doesn't want to be caught under the buzzer.

Explains Bucci, "Incentives are benefits in place to build wind farms here in Virginia. So, it's important for this budding industry that we extend these credits at the national level as well as well as all of our own state policies."

Environment Virginia says as of December 31st incentives which would help build wind turbines, such as these, will run out.


Environmental and health experts say this clean form of energy is where our cash strapped, fuel dependent nation should go.

"I'm concerned about protecting Virginia open spaces, but we need to develop renewable resources -energy resources as an alternatives to fossil fuels," explains former Roanoke City Council member Dr. Rupert Cutler.

But, wind farms aren't always popular.
A proposal to bring about 15-turbines to Poor Mountain in Roanoke County met mixed reviews last year.

"It doesn't seem that anywhere along the way we've looked at the ecological aspects," said Wind Project Opponent Ed Kinser in September 2011.

Wind Project Opponent Bert Bondurant agreed during that same interview in 2011, "And i have a concern that the board of supervisors doesn't fully appreciate the treasure that is esstenially in their trust to preserve."

Many are concerned about adding an eye sore on the ridge.
But, others say the area is far from untouched.

Says Sierra Club Conservation Chair Dan Crawford, "Poor mountain is not pristine. If you go up there that's where we have our antennas and microwave towers."

Many wonder the status of the Poor Mountain project.

Roanoke County Board of Supervisors Chairman Richard Flora says even though Roanoke County amended its zoning and set conditions for wind use, it hasn't heard from the group since those changes have been made.

Invenergy, the group behind the Poor Mountain plan, says it continues to "work on development plans" and looks forward to working in Virginia.

?

Read Invenergy's statement:

Statement from Invenergy ? November 28, 2012

Source: http://www.wdbj7.com/news/wdbj7-environmental-group-says-dont-blow-this-opportunity-when-it-comes-to-wind-energy-incentives-20121128,0,2454024.story?track=rss

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Source: http://www.humansthink.com/content/create-your-own-ecommerce-website

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Poison pens and lipstick guns: 8 real-life spy weapons

South Korean authorities capture an assassin armed with deadly gadgets almost as implausible as this collection of espionage gear

Newly crowned "Sexiest Man Alive" Kim Jong Un isn't the biggest fan of Park Sang-hak, an anti-Pyongyang defector now living in South Korea who's near the top of North Korea's hit list. The outspoken activist was recently the target of a would-be assassin equipped with three seemingly innocent, easy-to-conceal weapons plucked straight from a 007 script. A South Korea "investigation official," speaking with CNN, described the weapons thus: A poison-tipped device built to look like a Parker ballpoint pen; a second pen equipped to shoot poison-filled bullets directly into the skin; and a small flashlight rigged to fire three bullets at close range. "You'd notice a gun," said Park, "but these weapons are so innocuous [they could] easily kill someone [without warning]. I'd be dead immediately." Park is hardly the first to be the target of top-secret spy weaponry. Here, eight other imaginative killing devices that have actually been produced:?

1. Lipstick gun
Meet the "kiss of death." This famous Cold War-era pistol may look like an ordinary lipstick, but it was designed by KGB operatives to let a Soviet femme fatale fire a single 4.5mm bullet at anyone unlucky enough to get caught in her cross-hairs.?

2. Exploding rats
During World War II, Britain's Special Operations Executive (SOE) devised a clever plan to blow up enemy boilers by hiding explosive rat carcasses in German coal piles. Supposedly, an unsuspecting enemy would simply toss the dead rat into the nearby fire to dispose of the body and... kaboom! The plan went awry when German authorities seized the first consignment of the devices ? and went on to showcase them in the country's top military academies.

3. Flamethrower glove
Patrick Priebe, a cyberpunk weapons hobbyist, designed this hand-mounted flamethrower using just four lithium ion batteries, butane, a NE555 circuit board, and a transformer to spew fire right from his palm.?

4. Umbrella dart gun
Just one day before his 1978 death in London, Bulgarian dissident writer Georgi Markov felt a sharp prick in his thigh. He looked up to see a man clumsily fiddling with an umbrella before speeding off. The brolly had shot a dart loaded with a pellet of ricin, a sophisticated poison. The pellet was coated in a special wax designed to melt at body temperatures, releasing the ricin into the bloodstream. The shooter, believed to be a member of the Bulgarian secret police, was never caught.?

5. Exploding chocolate
Prime Minister Winston Churchill did not like the Nazis. And the Nazis did not like Prime Minister Winston Churchill, as evidenced by a letter written by a high-ranking World War II-era British intelligence officer, referencing a bizarre Nazi assassination plot to kill the boisterous politician with explosive chocolate. "We have received information that the enemy are using pound slabs of chocolate which are made of steel with a very thin cover of chocolate," wrote Lord Victor Rothschild of British intelligence. "Inside there is a high explosive and some form of delay mechanism." Fortunately, British spies discovered the candy bombs, which were to be placed around the War Cabinet's dining room, before anyone could have a taste.

6. Pistol glove
Another product of the Cold War-era KGB, this glove-cum-pistol be fired with the twitch of a finger. "It gave the wearer the ability to get within point blank range before firing a lethal shot," says Buck Sexton at The Blaze. "Oddjob would be proud."

7. Poisoned cigars
On August 16, 1960, a CIA official was handed a box of Fidel Castro's favorite cigars? along with instructions to rig them with a deadly poison. The cigars were treated with a toxin called botulinum, reportedly so potent it could kill any man who attempted to light one of the cigars. Though the cigars were duly doctored, it's unclear if they ever even made it into Castro's vicinity.?

8. CIA's heart-attack gun
During a mid-1970s Senate testimony, it was revealed that the CIA had developed a dart gun capable of causing a heart attack. The dart ? which could penetrate clothing, leave skin unmarked except for a small red bump resembling a mosquito bite, and then disintegrate ? was filled with a deadly shellfish toxin. The advantage, says InfoWars, was that officials would attribute the victim's death to natural causes in the event of an autopsy. It's unclear if the heart attack gun was actually ever used.?

Sources: CNN,?Wired, BBC, Gizmag, Cracked, The Atlantic, The Blaze, InfoWars

SEE ALSO: The 3D printing photo booth that turns you into an action figure

View this article on TheWeek.com Get 4 Free Issues of The Week

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Source: http://news.yahoo.com/poison-pens-lipstick-guns-8-real-life-spy-153400840.html

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Wednesday, November 28, 2012

Justin Bieber Overalls (PHOTO): Fashion Fail With Prime Minister

Yes, he is the biggest thing EVER to come out of Canada?eh? But the Justin Bieber overalls photo is hysterical ? and I can?t believe he would wear them to meet the Prime Minister. This owes him fashion fail of the utmost degree. Even scrappy, tattooed, herion-addict looking celebrities usually make an attempt at cleaning up if they are going to meet a dignitary. I think I?ve seen characters like Tommy Lee wearing suits ? even if they leave out the tie. So what if you are the biggest, most successful celebrity to come out of your country? Shouldn?t you at least throw on a button-up polo to meet the Prime Minister of said country? Sure. But my issue is not that he wore a ridiculous, striped, three-stooges outfit to accept a big award?.it?s that he wore it in the first place. One strap off, big, goofy hat on backwards and sideways, and a painfully ugly pair of shoes. Come on, Justin. You can do better. What do you think about the Justin Beiber overalls photo? Is it a total fail?

Source: http://feedproxy.google.com/~r/RightCelebrity/~3/JlD0CN6gtsc/

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Peru radio host still broadcasting for kids at 97

LIMA, Peru (AP) ? It was the golden age of radio and World War II still raged when Maruja Venegas began broadcasting a show for Peru's children.

Sixty-eight years later, her "Radio Club Infantil" is still on the air, making the 97-year-old Venegas the globe's longest-running radio personality, according to Guinness World Records.

"The children of yesterday are all grown now. They've married. They are grandparents today. So it's them, the grandparents, who support me most," she told The Associated Press in an interview in her home in a middle-class district of the capital.

"A lot of grandparents sit their grandchildren down to listen to the program," she said, stooped by age but still elegant with earrings and a camel-colored coat.

Venegas was a popular announcer on music programs when she launched the show on Dec. 18, 1944, at the request of government officials to entertain ailing children at a public hospital. The first commercial black and white television broadcasts were still more than a decade in the future for Peru. In the United States, "Fibber McGee and Molly" and "The Al Jolson Show" were going strong.

Venegas' show became so popular in the 1950s that it drew Peru's top singers and performers. It had contests, helped make careers. Listeners persuaded her to open a school in 1956. But when the country fell on hard times in the late 1980s, Venegas was forced to close it.

The show went on, however, even if Venegas began doing it by telephone from home when she reached age 90, and the program that once aired twice a week is now down to a single half-hour slot at 6 p.m. on Sundays, carried by Santa Rosa, a religion-oriented station. She still prepares her own programs, which always include a story, music, advice and commentary.

And she does it without pay, as she always has through the decades, making her living from other programs and jobs.

"My mother told me that I should never charge for Radio Club Infantil because it was for children and for the ill," Venegas recalled.

She could have used the money.

Venegas, who never married, has limited funds and like most people her age, physical limitations to address. She says she suffers from diabetes.

"I've lost eyesight. I can only see through one eye," she said. "But I remain optimistic"

She lives alone on an $870 a month pension that is not sufficient to support her and the 89-year-old sister with whom she lives. In order to pay the two people who care for them, she had to sell the second floor of her house.

Now, she's thinking of selling part of the first floor.

Source: http://news.yahoo.com/peru-radio-host-still-broadcasting-kids-97-180709674.html

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High performance Kia pro_cee'd GT set for 2013 launch | Car ...

?

The first glimpse of the Kia pro_cee?d GT reveals a hot hatch perfectly aligned with Kia?s sportiness and ?fun to drive? positioning.

Based on the all-new pro_cee?d which had its global debut at the 2012 Paris Motor Show, and will go on sale in the Spring next year, Kia?s first-ever hot hatch is expected to launch in the second half of 2013.

The pro_cee?d GT will feature a 1.6-litre turbocharged GDI engine mated to a six-speed manual transmission.

This entry was posted in Car and Van Insurance, car awards, Car Finance, car review, concept car, Eco Car, Kia Cars, Leasing, Main OSV News, motoring news, Vehicle Leasing and tagged Car launch, Car News, Car Review and Test Drive, kia, Kia Cee'd, Kia Ceed Lease, Kia Proceed. Bookmark the permalink.

Source: http://www.osv.ltd.uk/latestnews/main-osv-news/kia-pro_ceed-gt-for-2013-launch/

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Tuesday, November 27, 2012

Matt Damon Explains Why He Won't Play Lance Armstrong

Lance Armstrong's life story seems destined for the big screen, but it won't star Matt Damon. The Bourne Identity actor was recently rumored to be playing the disgraced cycling champion in an upcoming biopic, based on Armstrong's teammate's 2012 memoir The Secret Race. But in an interview with MTV News, Damon said that his bike-racing days are behind him.

Source: http://www.ivillage.com/why-matt-damon-wont-play-lance-armstrong/1-a-504738?dst=iv%3AiVillage%3Awhy-matt-damon-wont-play-lance-armstrong-504738

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Stock index futures signal slightly higher open

LONDON (Reuters) - Stock index futures pointed to a higher open on Wall Street on Tuesday, with futures for the S&P 500, the Dow Jones and the Nasdaq 100 rising 0.1 to 0.2 percent.

Market sentiment improved after Euro zone finance ministers and the International Monetary Fund clinched agreement late on Monday on reducing Greece's debt in a breakthrough to release urgently needed loans to keep the near-bankrupt economy afloat.

The Commerce Department releases October durable goods orders at 8.30 a.m. ET. Economists expect a 0.6 percent fall in orders in October, against a 9.8 percent rise in September.

ConocoPhillips' partners in Kazakhstan's Kashagan field have 60 days to exercise pre-emption rights to prevent India's ONGC Videsh from buying an 8.4 percent stake in the project held by the U.S. company, the Indian firm's managing director said.

ICSC/Goldman Sachs release chain store sales for the week ended November 24 at 7.45 a.m. ET. In the previous week, sales fell 0.3 percent.

Redbook releases its Retail Sales Index of department and chain store sales for November at 8.55 a.m. ET. In the prior period, sales were unchanged.

Standard & Poor's releases its S&P Case/Shiller Home Price Index for September at 9 a.m. ET. Economists expect an adjusted 20 city index to rise 0.4 percent, versus a 0.5 percent increase in the previous month.

Europe is preparing to follow the United States in delaying the introduction of stricter rules on bank capital, while it lobbies for a rethink of the U.S. stance, EU sources said.

However, the head of the Basel Committee at the Bank of International Settlements told Reuters on Tuesday that the introduction of stricter capital rules for banks will go ahead as planned on January 1.

Federal Reserve Bank of Chicago releases its Chicago Fed Midwest Manufacturing Index for October at 8.30 a.m. ET. The index read 93.4 in the prior month.

Conference Board releases November consumer confidence at 10 a.m. ET. Economists expect a reading of 73.0, compared with 72.2 in October.

The Federal Housing Finance Agency issues its Home Price Index for September at 10 a.m. ET. In the prior month, the index rose 0.7 percent.

European stocks <.fteu3> rose 0.5 percent on Tuesday, recovering after weakness in the previous session.

U.S. stocks slipped on Monday after posting their best week in over five months as investors reacted to a lack of visible progress in budget deficit discussions in Washington.

The Dow Jones industrial average <.dji> fell 77.92 points, or 0.60 percent, to 12,931.76. The S&P 500 Index <.spx> dropped 6.99 points, or 0.50 percent, to 1,402.16. The Nasdaq Composite Index <.ixic> shed less than a point at 2,966.75.

(Reporting by Atul Prakash; editing by Patrick Graham)

Source: http://news.yahoo.com/stock-index-futures-signal-slightly-higher-open-093032330--finance.html

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Parking Lot Car Accidents - It&#39;s That Time of Year - noyes legal news ...

Parking lot car accidentAutomobile accidents happen everywhere, but did you know that approximately 20 percent of car accidents happen in parking lots? With Christmas shopping season, the chances of being involved in a parking lot accident increases. However, there are ways to reduce the chances of a car accident in a parking lot.

One way to prevent a parking lot car accident is to be on lookout for bad drivers--those that cut across empty rows, drive too fast, or ignore signs and pavement markings. A driver needs to be extra cautious in parking lot to make up for those drivers that are less cautious.

For some reasons, pedestrians seem to be less watchful as they stroll to find their car. While looking for their car, they are not looking out for your vehicle. By anticipating pedestrians, you may be able to avoid crashing into them.

My favorite (and my wife's least favorite) is to simply to park as far away from other drivers as safely possible. It may be inconvenient, but we could all use the walk and it reduces the chances of a car accident.

Even if you take precautions, others may not causing you to be involved in a parking lot car accident. If that happens, here are a few things you should do:

  1. Notifying police or security. You will want a record of the crash for your insurance company.
  2. When a parking-lot accident first occurs, never admit it was your fault and don?t argue over who was at fault. Just exchange names, addresses, phone numbers and insurance information. You will never change their opinion at the accident scene.
  3. Find witnesses to the accident and ask whether they?d be willing to furnish a name or contact number. The location of the vehicles at the time of impact is important in establishing liability after a parking lot automobile accident.
  4. Take pictures--lots of them. Don?t move the vehicles until you take pictures. Photograph the skid marks, if any, along with broken glass or other debris.
  5. Although parking lot accidents don't typically cause huge property damage, they can still cause significant neck and back injuries--especially if the neck and back are turned when the car is struck. Make sure you see your doctor after any car accident, even a parking lot accident, to get checked out.

Enjoy Christmas shopping, but be safe in the parking lots and watch out for those who aren't.

-------------

Mathew Noyes 0050p
Personal Injury Attorney Matthew Noyes represents those injured in car accidents, motorcycle crashes, bicycle accidents, pedestrian accidents and other types of personal injury matters. His Clearwater law firm ? Perenich Caulfield Avril Noyes ? is one of the oldest personal injury law firms in Pinellas County. Call Attorney Matthew Noyes now at 727-796-8282 or simply click here to schedule a free case consultation.

Source: http://matthewnoyes.typepad.com/attorney_matthew_noyes_bl/2012/11/parking-lot-car-accidents-its-that-time-of-year.html

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Maryland Alcohol Sales Stagnant: Where Will You Get Your ...

?

Sales of distilled spirits have increased only .2 percent in Maryland since last year?far below the national average of 3.1 percent, according to figures stated in a recent Washington Post blog post.

The post cites the Distilled Council of the United States, which linked the stagnating sales to the increase in taxes on?alcohol?from 6 percent to 9 percent.

The chief economist for the council, David Ozgo, is quoted as stating that ?Maryland consumers are voting with their feet and making their purchases in Delaware.?

A Capital News Service article reported that sales of distilled spirits near the border of Maryland and Delaware in Cecil County are down 57 percent.

Do you venture to other states like Delaware to purchase alcohol?

Source: http://hyattsville.patch.com/articles/driving-for-drink-booze-sales-in-maryland-stagnant-in-2012-up-in-nearby-delaware

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Monday, November 26, 2012

GOP senator: It's fair to put idea of raising revenues on table as part of fiscal cliff talks (Star Tribune)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/266220657?client_source=feed&format=rss

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California Headphones Laredo review

Everyone who is sick of hip-hop branded earphones that rattle the brain with ?ber bass, mentally raise your hand. The people responsible for California Headphones obviously feel that way because they did something about it with the Laredo (which is reviewed here) and Silverado headphones. Both are specially tuned for rock and country music. Their [...]

Source: http://the-gadgeteer.com/2012/11/24/california-headphones-laredo-review/

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Of bargains: grand and not so much

Bargaining is a big part of life. It is how prices are set, business deals get made, and political differences are hashed out. Sometimes you get the advantage, sometimes not -- and often it's the bargain itself that's memorable.

By John Yemma,?Editor / November 26, 2012

A rug merchant waits for customers at the Mecca market in Riyadh, Saudi Arabia.

Ayez Nureldine/AFP/Getty Images/File

Enlarge

A?hot wind blew off the Red Sea. Along with a dozen other reporters, I was camped out in an air-conditioned foyer at a royal palace in Jeddah, Saudi Arabia, waiting for the Saudi foreign minister and the US secretary of State to emerge from crisis meetings in the weeks before the 1991 Gulf War. Hours ticked by. Reporters dozed. Somewhere near dawn, our Saudi handlers ushered in a rug merchant to distract us with his goods.

Skip to next paragraph John Yemma

Editor, The Christian Science Monitor

John Yemma has been a foreign correspondent, Washington reporter, political editor, and has covered economics, science, and culture in 38 years as a journalist. He has worked for The Dallas Morning News, The Boston Globe, UPI, The San Antonio Express-News -- and since 2008, he has been Editor of the Monitor. The Monitor?publishes international news and analysis at CSMonitor.com, in the Monitor Weekly newsmagazine, and in an email-delivered Daily News Briefing.?

Recent posts

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I was a tough but seasoned bargainer, tossing out the word ?soumak? when he unrolled a flat-woven rug. Not to be taken for a rube, I began decisively, cutting the offering price of the tribal textile in half, all the while staying cordial with my new ?friend.? I knew when to act miffed, when to say I could go no higher, and when to give ground.

?Mabrouk,? the merchant said, pumping my hand as we finally closed the deal. ?Congratulations, sir. You bargain well and have excellent taste.?

I got my prize, plus a small brass coffeepot ? and something even better: a great story. Robin, my wife and artistic director, had taught me to look for that tribal rug design. I had watched her 10 years earlier drive a hard bargain in the Hamidiya souk of Damascus, so this would be an excellent ?Hi, honey, I?m home!? trophy. I could see my carefully acquired soumak spread out under the coffee table.

One day, I imagined, someone might ask the intrepid foreign correspondent if there was a story behind that rug. Well, yes,
?ha-ha, now that you ask: A hot wind blew off the Red Sea....

Some weeks later, I unpacked my bags, and Robin examined the rug. She seemed to admire the style. I told her about the negotiations, the back-and-forth drama, and the hearty ?Mabrouk? that sealed the deal.

?Nice to have you home, dear,? she said.

The rug was placed under the table. A few days later, somebody spilled a tumbler of water on it. The colors ran, burgundy flowing into beige, brown into ochre. The wool puckered, and forever afterward the not-so-valuable and certainly-not-old dust catcher was known as ?John?s famous mabrouk soumak.?

Our dogs enjoyed it. Goodwill eventually accepted it.

The larger point? Negotiations are tricky. Prices and values are not objective facts but markers of give and take, set by us when we engage with each other. When we negotiate, we know our starting position but cannot dictate the outcome.

Congress and the president of the United States are engaged in an epic negotiating session to try to figure out how much government should spend and tax and how to avoid plunging off the Jan. 1 ?fiscal cliff.? The Monitor?s David Grant has dug deeply into the issues and explained them clearly and calmly in a recent Monitor cover story.?

Psychologists say that when you are negotiating, the important thing is to clearly articulate what you want, remain open-minded and genial, and be ready to make a deal. You may not get what you thought you wanted, but you don?t get anything by refusing to bargain. I wanted an impressive trophy. I got something that has lasted much longer: a story.

John Yemma is editor of The Christian Science Monitor.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/YvyGcTKwVKI/Of-bargains-grand-and-not-so-much

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Sunday, November 25, 2012

Afghan police: Student killed in university clash

KABUL, Afghanistan (AP) ? Sunni and Shiite students clashed at Kabul University on a Shiite holy day Saturday, and Afghan authorities say that one person was killed.

Gen. Mohammad Zahir, director of the criminal investigation division, said police were trying to assess why the fight that broke out in the afternoon, killing one student and wounding six others.

An Associated Press reporter at the scene said Shia and Sunni students started fighting and by evening, several hundred more people joined the melee, fist-fighting and throwing stones at each other. He said eyewitnesses at the scene said the clash was related to Ashoura, the commemoration of the 7th century death of the Prophet Mohammad's grandson.

Afghan leaders went to the site to try to calm the crowd. Abdul Azim Nurbakhsh, a spokesman for the Ministry of Higher Education, said late Saturday that classes at the university had been canceled for the next 10 days. Damage was reported to buildings at the university.

Other gatherings marking Ashoura in the Afghan capital were peaceful, but last year, a suicide bomber on foot struck worshippers at a Shiite shrine in Kabul, killing at least 80 people. Some Sunni extremists consider Shiite ceremonies to be heretical.

Separately, NATO said a service member with the international military coalition was killed Saturday in an insurgent attack in the south.

No other information was disclosed.

So far this year, 379 NATO service members have died in Afghanistan.

___

Associated Press Writer Massieh Neshat in Kabul contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2012-11-24-AS-Afghanistan/id-8956337b052a4b03a371092d3339b25d

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Black Friday Guide For Gay Shoppers: HRC's Buyer's Guide Ranks Brands' Corporate Equality

Great news for holiday shoppers who will be hitting Abercrombie & Fitch, Starbucks and Target this Black Friday: all three companies get top rankings in the new Human Rights Campaign (HRC) Foundation's Buyer's Guide.

The report, also titled "Buying for Workplace Equality 2013," divides popular businesses and their related products into three categories based on their score on the HRC Foundation?s Corporate Equality Index. With a score of 100, Abercrombie & Fitch and Target rank alongside General Mills and Kellogg's as being among the businesses and brands to receive the highest workplace equality scores.

On the flip side, the Trump Organization, Urban Outfitters and even Tupperware received considerably less favorable ratings, placing them among the report's businesses/brands to receive the lowest workplace equality scores.

?It?s not often people think of ?Black Friday? as an occasion to take a stand for LGBT equality, but the HRC Buyers? Guide is the tool fair-minded consumers need to do just that,? HRC President Chad Griffin said in an email statement. ?With historic electoral wins for equality earlier this month, it is clear Americans care about how companies treat their LGBT workers.?

Check out the full rankings here.

See a selection of the rankings below:

  • Abercrombie & Fitch

    Rank: 100, or among businesses/brands to receive HRC's highest workplace equality scores.

  • Gap

    100, or among businesses/brands to receive our highest workplace equality scores.

  • Nike

    100, or among businesses/brands to receive HRC's highest workplace equality scores.

  • Burberry

    15, or among businesses/brands that receive HRC's lowest workplace equality scores.

  • Urban Outfitters

    15, or among businesses/brands to receive HRC's lowest workplace equality scores.

  • Target

    100, or among businesses/brands to receive our highest workplace equality scores.

  • Home Depot

    75, or among businesses/brands to receive a moderate workplace equality score.

  • IKEA

    30, or among businesses/brands to receive HRC's lowest workplace equality scores.

  • Coca-Cola Enterprises

    100, or among businesses/brands to receive HRC's highest workplace equality scores.

  • Starbucks

    90, or among businesses/brands to receive HRC's highest workplace equality scores.

  • Hershey

    85, or among businesses/brands to receive HRC's highest workplace equality scores.

  • The Walt Disney Company

    100, or among businesses/brands that receive HRC's highest workplace equality scores.

  • Trump Organization

    0, or among businesses/brands that receive HRC's lowest workplace equality scores.

  • McDonald's

    75, or among businesses/brands to receive a moderate workplace equality score.

  • Cracker Barrel Old Country Store

    35, or among businesses/brands that receive HRC's lowest workplace equality scores.

  • Domino's Pizza

    35, or among businesses/brands that receive HRC's lowest workplace equality scores.

  • Burger King

    55, or among businesses/brands to receive a moderate workplace equality score from HRC.

  • Hallmark

    90, or among businesses/brands that receive HRC's highest workplace equality scores.

  • Mattel

    85, or among businesses/brands that receive HRC's highest workplace equality scores.

  • Hasbro

    25, or among businesses/brands that receive HRC's lowest workplace equality scores.

See a selection of the results in the slideshow below:

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Source: http://www.huffingtonpost.com/2012/11/23/hrc-buyers-guide-lgbt-shoppers_n_2177457.html

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Saturday, November 24, 2012

Kiplinger&#39;s Personal Finance - January 2013 Free Downloads ...

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Kiplinger's Personal Finance - January 2013

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Kiplinger's Personal Finance was written to help you do a better job of managing your personal and family financial affairs and to help you get more for your money. You get ideas on saving, investing, cutting taxes, making major purchases, advancing your career, buying a home, paying for education, health care and travel, plus much, much more.

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